Children Exposed: Biomonitoring Can Provide a Baseline

Setting a Baseline for Biomonitoring

Biomonitoring of Perfluorinated Compounds in Children and Adults Exposed to Perfluorooctanoate-Contaminated Drinking Water

OBJECTIVE 40,000 residents in Arnsberg, Germany, had been exposed to drinking water contaminated with perfluorinated compounds (PFCs). Internal exposure of the residents of Arnsberg to six PFCs was assessed in comparison with reference areas. DESIGN AND PARTICIPANTS One hundred seventy children (5-6 years of age), 317 mothers (23-49 years), and 204 men (18-69 years) took part in the cross-sec...

Can laboratory animal carcinogenicity studies predict cancer in exposed children?

A key to the prevention of childhood cancer is the control of carcinogens to which children are exposed. The first step in this process is to identify those chemicals that are likely to cause cancer in children. The best way to identify carcinogens, today, is the use of the rodent lifetime cancer test--the bioassay. The test has vocal critics, but is adequately reliable if properly used. Perhap...

Biomonitoring of Toxic Effects of Pesticides in Occupationally Exposed Individuals

BACKGROUND Workers in pesticide manufacturing industries are constantly exposed to pesticides. Genetic biomonitoring provides an early identification of potential cancer and genetic diseases in exposed populations. The objectives of this biomonitoring study were to assess DNA damage through comet assay in blood samples collected from industry workers and compare these results with those of clas...

Biomonitoring of traffic police officers exposed to airborne platinum.

BACKGROUND Over the past two decades there has been a substantial increase in environmental levels of palladium, platinum, and rhodium, the platinum group elements (PGEs), due to the widespread use of catalytic converters for automotive traction. AIM To evaluate urinary platinum levels in occupationally exposed subjects. METHODS A total of 161 employees from the Rome City Police Force were ...